SMi Drug Discovery
SMi Drug Discovery has developed a transformational, new, optical technology that will have far-reaching benefits in the fields of diagnosis and drug discovery. SMi’s technology is a variant of super resolution microscopy, an area which was the subject of Nobel Prizes in 2014 and 2017. SMi have been awarded a non-dilutive £1.9M UK Innovation grant for the development of their platform for virus diagnosis in large central laboratories.
The system can identify and count individual virus in a sample in 50 milliseconds, with a sensitivity equivalent to the gold standard PCR tests. SMi’s technology complements Aurem’s in that is designed for large central locations.
SMi’s platform’s second application is in speeding up drug discovery where cutting a year off development can save > $100 million. During drug development, scientists need to know how a drug binds to its target, exactly where and for how long. SMi’s technology is revolutionary as it can visualise hundreds of thousands of these interactions whereas current techniques provide only average data. A good analogy is that current techniques are like trying to determine the exact composition of traffic from the noise of vehicles whereas, SMi’s technology photographs and counts every bus, car, lorry and bike.